Detalhe da pesquisa
1.
Statins affect human iPSC-derived cardiomyocytes by interfering with mitochondrial function and intracellular acidification.
Basic Res Cardiol
; 119(2): 309-327, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38305903
2.
Placental disposition of eculizumab, C5 and C5-eculizumab in two pregnancies of a woman with paroxysmal nocturnal haemoglobinuria.
Br J Clin Pharmacol
; 87(4): 2128-2131, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32986871
3.
Toxicity of anticancer drugs in human placental tissue explants and trophoblast cell lines.
Arch Toxicol
; 95(2): 557-571, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33083868
4.
Placental transfer of tofacitinib in the ex vivo dual-side human placenta perfusion model.
Curr Res Toxicol
; 6: 100149, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38292667
5.
Physiologically-Based Pharmacokinetic Modelling to Predict the Pharmacokinetics and Pharmacodynamics of Linezolid in Adults and Children with Tuberculous Meningitis.
Antibiotics (Basel)
; 12(4)2023 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37107064
6.
Transport of the coumarin metabolite 7-hydroxycoumarin glucuronide is mediated via multidrug resistance-associated proteins 3 and 4.
Drug Metab Dispos
; 40(6): 1076-9, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22415933
7.
Exploiting transport activity of p-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists.
Mol Pharm
; 9(5): 1351-60, 2012 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22428727
8.
Effects of tumor necrosis factor on undifferentiated and syncytialized placental choriocarcinoma BeWo cells.
Toxicol In Vitro
; 80: 105327, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35134484
9.
Prediction of Moxifloxacin Concentrations in Tuberculosis Patient Populations by Physiologically Based Pharmacokinetic Modeling.
J Clin Pharmacol
; 62(3): 385-396, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34554580
10.
Cannabinoid type 1 receptor antagonists modulate transport activity of multidrug resistance-associated proteins MRP1, MRP2, MRP3, and MRP4.
Drug Metab Dispos
; 39(7): 1294-302, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21511945
11.
Rosuvastatin increases extracellular adenosine formation in humans in vivo: a new perspective on cardiovascular protection.
Arterioscler Thromb Vasc Biol
; 29(6): 963-8, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19359665
12.
Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice.
Biochim Biophys Acta Mol Basis Dis
; 1866(6): 165727, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32070771
13.
Intra-arterial AICA-riboside administration induces NO-dependent vasodilation in vivo in human skeletal muscle.
Am J Physiol Endocrinol Metab
; 297(3): E759-66, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19602584
14.
Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs.
Eur J Pharm Sci
; 115: 175-184, 2018 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29309877
15.
Enhanced cellular adenosine uptake limits adenosine receptor stimulation in patients with hyperhomocysteinemia.
Arterioscler Thromb Vasc Biol
; 25(1): 109-14, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15539618
16.
Oral therapy with dipyridamole limits ischemia-reperfusion injury in humans.
Clin Pharmacol Ther
; 78(1): 52-9, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16003293
17.
In vivo evidence against a role for adenosine in the exercise pressor reflex in humans.
J Appl Physiol (1985)
; 99(2): 522-7, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15817726
18.
Impaired endothelium-dependent vasodilation does not initiate the development of sunitinib-associated hypertension.
J Hypertens
; 33(10): 2075-82, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26203967
19.
Proximal tubular efflux transporters involved in renal excretion of p-cresyl sulfate and p-cresyl glucuronide: Implications for chronic kidney disease pathophysiology.
Toxicol In Vitro
; 29(7): 1868-77, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26216510
20.
Renal glucuronidation and multidrug resistance protein 2-/ multidrug resistance protein 4-mediated efflux of mycophenolic acid: interaction with cyclosporine and tacrolimus.
Transl Res
; 164(1): 46-56, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24486136